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Chris Macklin
Colorectal Surgeon

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Chris Macklin Doctor of Medicine Thesis 2004

1.a. The association of diet and cancer

1.b. Colorectal cancer

1.c. The aetiology of colorectal cancer and adenomatous polyps

1.d. Colorectal cancer and screening

6. Primary Hypothesis

7. Aims

8. Methods

2.a. The FlexiScope Trial

2.b. Data collection

2.c. DNA Extraction

2.d. NAT1 Genotype Analysis

2.e. NAT2 Genotype Analysis

2.f. Collaboration with other centres

2.g. Statistical analysis

2.h. Cleaning the FFQ data

9. Results

3. Leeds Flexiscope Trial Results

4. Cases and Controls

5. N-acetyltransferase Genotype

6. Smoking

7. Measures of Meat Exposure

10. Discussion & Conclusions

7. N-acetyltransferase Genotype

8. Smoking

9. Measures of Meat Exposure

10. Confounding Factors for Multivariate Analysis

11. Summary

11. Appendices

Appendix 1: Arylamine N-Acetyltransferase Nomenclature

Appendix 2: Ethics Committee Approval

Appendix 3: Initial Questionnaire

Appendix 4: Invitation Letters

Appendix 5: Guidelines for using the enema

Appendix 6: Pre-Screening Medical Form

Appendix 7: Screening Findings

Appendix 8: Endoscopic Pathology Report

Appendix 9: Colonoscopy Findings

Appendix 10: Information and Consent Forms for Blood Taking

Appendix 11: FlexiScope Consent Form

Appendix 12: Food Frequency Questionnaire

Appendix 13: Post-Exam Questionnaire

Appendix 14: Glossary of Abbreviations

12. References

Last modified: 29 Dec 2006 00:09
Authored in CALnet

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